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What Next | Daily News and Analysis


What Next | Daily News and Analysis

What the Hell is a Peptide?

Thu, 30 Jul 2026

On the heels of the success of GLP-1s like Ozempic, other peptide treatments are flooding the marketplace—and advertising spaces. But even as the Trump administration’s FDA discusses approving more treatments and the businesses selling them proliferate, many peptides are sitting in a legal and medical gray area. So how real - and safe - is this peptide hype?


Guest: Kate Knibbs, senior writer at WIRED.


Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.


Podcast production by Rob Gunther, Evan Campbell, Madeline Thames-Ducharme and Patrick Fort.


Paige Osburn is the senior supervising producer of What Next and What Next TBD.


Hosted on Acast. See acast.com/privacy for more information.

Trump's Forever War

Wed, 29 Jul 2026

The US can’t leave Iran in charge of the Strait of Hormuz, but it can’t wrestle control away without committing ground troops—but it also can’t keep going on like this. So where does that leave everyone?


Guest: Josh Keating, senior correspondent covering foreign affairs at Vox. 


Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.


Podcast production by Rob Gunther, Evan Campbell, Madeline Thames-Ducharme and Patrick Fort.


Paige Osburn is the senior supervising producer of What Next and What Next TBD.


Hosted on Acast. See acast.com/privacy for more information.

The DSA's Biggest Hater Likes One of Their Policies

Tue, 28 Jul 2026

In the wake of the success among members of the Democratic Socialists of America, The Atlantic’s Jonathan Chait has turned in a series of articles that call the group anti-democratic, against the Democratic Party, and unnecessary or even a hindrance to accomplishing policy goals like universal health care. On the other hand, he thinks DSA member Zohran Mamdani is doing a pretty good job as mayor so far. 


So what’s at the root of Chait’s problem with the DSA? And what policy position is he completely on board with? 


Guest: Jonathan Chait, staff writer at The Atlantic.


Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.


Podcast production by Rob Gunther, Evan Campbell, Madeline Thames-Ducharme and Patrick Fort.


Paige Osburn is the senior supervising producer of What Next and What Next TBD.


Hosted on Acast. See acast.com/privacy for more information.

How Charlie Kirk Went From Martyr to Meme

Mon, 27 Jul 2026

In the immediate aftermath of Charlie Kirk’s murder, the NFL was holding moments of silence, Ezra Klein was waxing about how he was ‘practicing politics the right way,” and criticizing Kirk online could get you fired. Now, as the trial of Tyler Robinson, Kirk’s alleged killer, begins, something has replaced that reverence. 


Guest: Will Sommer, senior reporter for the Bulwark and writer of False Flag, a newsletter about the online culture and communities now running our country. 



Want more What Next? Subscribe to Slate Plus to access ad-free listening to the whole What Next family and across all your favorite Slate podcasts. Subscribe today on Apple Podcasts by clicking “Try Free” at the top of our show page. Sign up now at slate.com/whatnextplus to get access wherever you listen.


Podcast production by Rob Gunther, Evan Campbell, Madeline Thames-Ducharme and Patrick Fort.


Paige Osburn is the senior supervising producer of What Next and What Next TBD.


Hosted on Acast. See acast.com/privacy for more information.

Off-the-Record: Wait, You Ran THAT Boston Marathon?

Fri, 24 Jul 2026

Why are kids getting faster? Is it the shoes? Also, running the Boston Marathon is obviously a huge accomplishment, but if you ran the 2013 Boston Marathon, you should lead with that and not save it for an interview years after you meet someone.


Guest: Rob Gunther, producer for Slate’s What Next.


This episode is member-exclusive. Listen to it now by subscribing to Slate Plus. By joining, not only will you unlock exclusive episodes of What Next —you’ll also access ad-free listening across all your favorite Slate podcasts. You can subscribe directly from the What Next show page on Apple Podcasts and Spotify. Or, visit slate.com/whatnextplus to get access wherever you listen.


Podcast production by Rob Gunther, Evan Campbell, Madeline Thames-Ducharme and Patrick Fort.


Paige Osburn is the senior supervising producer of What Next and What Next TBD.


Hosted on Acast. See acast.com/privacy for more information.

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